1332 Diarrhea, Heartburn, and Recurrent Pancreatitis: An Interesting Presentation of Zollinger-Ellison Syndrome
نویسندگان
چکیده
منابع مشابه
An Unusual Presentation of Zollinger-Ellison Syndrome
Zollinger-Ellison syndrome is an often progressive, persistent and frequently life-threatening disease, described for the first time as characterized by ulceration of the upper jejunum, hypersecretion of gastric acid and non-beta islet cell tumors of the pancreas; this syndrome is due to the hypersecretion of gastrin. We report a case of Zollinger-Ellison syndrome presenting as severe esophagit...
متن کاملZollinger-Ellison Syndrome — Presentation, Diagnosis, Therapy
Zollinger-Ellison syndrome results from a pancreatic tumor in the non-beta islet cells, which stimulates the maximal activity of the gastric acid-secreting cells, resulting in gastrointestinal ulceration of the mucosa. Multiple endocrine neoplasia type 1 (MEN 1) is a familial autosomal dominant syndrome that includes Zollinger-Ellison syndrome as part of it; however, Zollinger-Ellison syndrome ...
متن کاملZollinger-Ellison syndrome
Since Zollinger and Ellison described in 1955 a pathological entity consisting of multiple recurrent peptic ulcerations, gastric hypersecretion, and islet cell tumours of the pancreas, several reports have been published dealing with the clinical and biological aspects of this new syndrome (Priest and Alexander, 1957;Summerskill, 1959; Gregory,Tracy, French, and Sircus, 1960; Grossman, Tracy, a...
متن کاملZollinger-Ellison Syndrome: A Rare Case of Chronic Diarrhea
Zollinger-Ellison syndrome (ZES) is caused by hypersecretion of gastrin from duodenal or pancreatic gastrinomas. We report a case of a 57-year-old female who presented with chronic diarrhea. CT abdomen showed multiple liver masses. Liver biopsy suggested metastatic well-differentiated neuroendocrine tumor. Serum gastrin level was markedly elevated. MRI abdomen, somatostatin receptor scintigraph...
متن کاملZollinger-Ellison Syndrome
Epidemiology The incidence of gastrinomas is 0.5-2/million population/year. [3] 20-30% of patients have ZES as part of MEN1, an autosomal dominant disorder. [4] Mean age of presentation is around 40, being younger in MEN1 patients than sporadic cases. Only about 3% present before age 20 and 7% after age 60. Gastrinomas are the most common functioning tumour of the pancreas. In addition to secre...
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ژورنال
عنوان ژورنال: American Journal of Gastroenterology
سال: 2019
ISSN: 0002-9270,1572-0241
DOI: 10.14309/01.ajg.0000594856.27576.b4